Additional Information

Description

Zynrelef 400 mg Extended-Release Solution is a post-surgical analgesic designed to provide prolonged pain relief for up to 72 hours following surgical procedures. It is specifically indicated

for use in adults undergoing soft tissue and orthopedic surgeries, including foot and ankle procedures and other orthopedic surgeries such as total joint arthroplasty, provided direct exposure to articular cartilage is avoided.

The active ingredients in Zynrelef include bupivacaine and meloxicam, which work synergistically to provide extended pain relief. Bupivacaine is a local anesthetic that blocks nerve signals in the area of administration, while meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain. The combination of these two agents ensures both immediate and sustained pain control, improving post-surgical recovery and patient comfort.

Zynrelef is administered as a single dose directly into the surgical site by a healthcare professional during the procedure. Its extended-release formulation allows for a controlled release of the active ingredients over a 72-hour period, minimizing the need for additional pain relief medications and potentially reducing opioid use in post-operative care.