Additional Information

Description

Vitamin D3 Capsules 50,000 IU contain cholecalciferol, a fat-soluble vitamin essential for calcium and phosphate regulation in the body. It plays a critical role in bone health by enhancing calcium absorption in the intestines and maintaining serum calcium and phosphate levels for proper bone mineralization. It is commonly prescribed for individuals with severe vitamin D deficiency, osteoporosis, or conditions that impair vitamin D metabolism.

The mechanism of action involves conversion into calcidiol in the liver and then into the active form, calcitriol, in the kidneys. Calcitriol binds to vitamin D receptors, promoting calcium transport and bone formation. It also modulates immune function and reduces inflammation, contributing to overall health beyond skeletal benefits.

Possible side effects include hypercalcemia, nausea, vomiting, fatigue, and kidney stone formation. Long-term excessive intake may lead to toxicity, characterized by confusion, arrhythmias, and renal impairment. Caution is required in patients with hyperparathyroidism, renal disorders, and sarcoidosis due to the risk of increased calcium levels.