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Description
Valproate 500mg/5mL SDV is a sterile injectable solution containing sodium valproate, an anticonvulsant and mood-stabilizing agent. It is supplied in single-dose vials, with each vial providing 500mg of the active ingredient in 5mL of solution. This formulation is designed for intravenous administration in patients requiring rapid therapeutic levels of valproate, particularly when oral administration is not feasible.
The primary mechanism of action of valproate involves the enhancement of gamma-aminobutyric acid (GABA) activity in the central nervous system. By increasing GABA availability, it helps to stabilize neuronal activity and reduce the occurrence of seizures. Valproate also has effects on voltage-gated sodium channels, further contributing to its antiepileptic properties.
Valproate 500mg/5mL SDV is typically administered by healthcare professionals in a controlled clinical setting. The dosage is individualized based on the patient’s condition, therapeutic needs, and tolerability. Frequent monitoring of valproate serum levels, liver function, and platelet counts is recommended during therapy to avoid potential toxicity and complications.
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