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Description
Sulfacetamide Lotion 10% (118 mL) is a topical antibiotic used to treat a variety of skin conditions, including acne vulgaris, rosacea, and seborrheic dermatitis. The lotion contains sulfacetamide sodium, a sulfonamide antibiotic that works by inhibiting bacterial growth. It is particularly effective against skin bacteria, such as Propionibacterium acnes, which contribute to acne development and inflammation.
The mechanism of action involves the inhibition of dihydropteroate synthase, an enzyme involved in the synthesis of folic acid. By blocking this pathway, sulfacetamide prevents bacteria from producing necessary compounds, ultimately reducing their growth and the inflammatory response. This action helps in treating bacterial infections that exacerbate conditions like acne and rosacea.
Common side effects may include skin irritation, dryness, or peeling at the application site. Allergic reactions, although rare, can occur and may present as redness, swelling, or severe irritation. It is important to avoid use on open wounds or broken skin, as it may lead to further irritation.
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