Product Details

Injections: Propofol Injection, 1% SDV, 10 x 100 mL

Manufacturer: Sagent

MFG#: 25021-0608-51

NDC: 25021-0608-51

PID: 418169

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Additional Information

Product NamePropofol 1% SDV 10X100 mL
Concentration1% propofol emulsion (10 mg of propofol per mL)
Administration RouteIntravenous (IV) injection
Mechanism of ActionEnhances the activity of gamma-aminobutyric acid (GABA) receptors in the brain, leading to sedative and hypnotic effects
Onset of ActionRapid onset of anesthesia, typically within 30 to 60 seconds after administration
Duration of ActionShort duration, allowing for rapid recovery and quick awakening once infusion is discontinued
UsageEffective for immediate sedation and for maintaining sedation during extended periods of mechanical ventilation
Storage RequirementsStore at controlled room temperature, protect from light
PackagingPack of 10 single-dose vials (SDV), each containing 100 mL of solution
IndicationsInduction and maintenance of anesthesia in surgical and diagnostic procedures; sedation of mechanically ventilated patients in intensive care settings

Description

Propofol 1% SDV 10X100 mL is a widely used intravenous anesthetic agent known for its rapid onset and short duration of action. Each single-dose vial (SDV) contains a 1% propofol emulsion, equating to 10 mg of propofol per mL, and the product is supplied in a pack of 10 vials, each containing 100 mL. This formulation is specifically designed for inducing and maintaining anesthesia in both surgical and diagnostic procedures.

The pharmacological action of propofol involves enhancing the activity of gamma-aminobutyric acid (GABA) receptors in the brain, which leads to sedative and hypnotic effects. This mechanism allows for a quick onset of anesthesia, typically within 30 to 60 seconds after administration, making it highly effective for procedures requiring immediate sedation. Propofol's short duration of action facilitates rapid recovery, enabling patients to awaken quickly once the infusion is discontinued.

Propofol 1% is also utilized in intensive care settings for the sedation of mechanically ventilated patients. Its properties ensure that it provides effective sedation without significant accumulation in the body, even with prolonged use. This makes it a preferred choice for maintaining patient comfort and safety during extended periods of ventilation.

Frequently Asked Questions (FAQs)

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Injections: Propofol Injection, 1% SDV, 10 x 100 mL is manufactured by Sagent.

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