Additional Information

Description

Prochlorperazine 25 mg suppositories are a prescription medication used primarily for the management of severe nausea and vomiting. As a phenothiazine derivative, prochlorperazine functions as a dopamine receptor antagonist, exerting antiemetic effects by blocking dopamine activity in the chemoreceptor trigger zone of the brain. This action reduces nausea and vomiting associated with various medical conditions, including postoperative recovery, chemotherapy, and severe vertigo.

Prochlorperazine is used in the treatment of schizophrenia and other psychotic disorders. It helps control symptoms by modulating dopamine levels in the central nervous system, which can contribute to symptom relief in patients with schizophrenia. The suppository formulation provides an alternative route of administration for patients unable to take oral medications due to persistent vomiting or other gastrointestinal conditions.

Common side effects of prochlorperazine include drowsiness, dizziness, dry mouth, and constipation. Serious adverse reactions, such as extrapyramidal symptoms or neuroleptic malignant syndrome, may occur in rare cases. Caution is advised in elderly patients and those with underlying neurological disorders.