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Description
Methotrexate 2.5 mg tablet is an immunosuppressive and anticancer medication used to treat a variety of conditions, including rheumatoid arthritis, psoriasis, and certain types of cancer, such as leukemia and osteosarcoma. Methotrexate works by inhibiting the enzyme dihydrofolate reductase, which is necessary for DNA synthesis and cell division. This action disrupts the growth of rapidly dividing cells, including both cancerous cells and immune cells that cause inflammation in autoimmune diseases.
For rheumatoid arthritis, methotrexate is commonly prescribed as part of a disease-modifying antirheumatic drug (DMARD) regimen. It helps to reduce joint inflammation, pain, and damage by suppressing the immune system's abnormal response. In the treatment of psoriasis, methotrexate slows down the overproduction of skin cells, alleviating symptoms and improving skin appearance.
Methotrexate is usually taken orally, with the dosage adjusted based on the patient's condition and response to treatment. It may be taken once weekly for autoimmune diseases, while cancer treatment schedules vary. Methotrexate has potential side effects, including nausea, liver toxicity, bone marrow suppression, and gastrointestinal issues.
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