Additional Information

Description

Meperidine 100 mg/mL is an injectable opioid analgesic used for the management of moderate to severe pain. It is a synthetic narcotic with properties similar to morphine but with a shorter duration of action. The medication is supplied as a sterile, single-dose vial containing 100 mg of meperidine hydrochloride per milliliter in a clear solution. It is intended for intramuscular or subcutaneous administration and is commonly used in clinical settings where short-term pain relief is necessary.

The mechanism of action of meperidine involves binding to opioid receptors in the central nervous system, inhibiting the transmission of pain signals. Its analgesic effects are accompanied by sedative and respiratory depressant properties, making careful monitoring essential during administration. Meperidine is rapidly absorbed and metabolized, with its peak effect occurring within 15 to 20 minutes after injection.

Meperidine is indicated for acute pain relief, postoperative pain, and certain procedural settings. It may also be used for preoperative sedation or to manage pain in obstetric scenarios. However, its use is limited due to the risk of accumulation of toxic metabolites, such as normeperidine, which can cause central nervous system excitation, seizures, and neurotoxicity.