Additional Information

Description

Loperamide 2 mg tablets are an over-the-counter medication used for the symptomatic treatment of diarrhea. It is particularly effective in managing acute non-specific diarrhea and chronic diarrhea associated with inflammatory bowel disease (IBD). Loperamide works by slowing the movement of muscles in the gut, thereby reducing the frequency of bowel movements and allowing more time for water absorption, which leads to firmer stools.

The mechanism of action of loperamide involves binding to opioid receptors in the intestinal wall. This action inhibits the release of acetylcholine and prostaglandins, which results in reduced peristalsis and increased transit time in the intestines. By decreasing gut motility, loperamide helps to control the symptoms of diarrhea, improving stool consistency and reducing urgency.

Loperamide is typically dosed as 2 mg tablets, with an initial dose.The recommended dose for adults is usually 4 mg initially, followed by 2 mg after each loose stool, with a maximum daily dose of 8 mg. Common side effects include constipation, abdominal discomfort, and nausea.