Additional Information

Description

Gentamicin 10 mg/mL, 2 mL Pediatric Single-Dose Vial (SDV), is an aminoglycoside antibiotic formulated for parenteral administration. It is used primarily for the treatment of serious bacterial infections caused by susceptible strains of gram-negative and some gram-positive organisms. The medication acts by binding to the 30S subunit of bacterial ribosomes, thereby inhibiting protein synthesis and leading to bacterial cell death.

This formulation is specifically designed for pediatric use, with a concentration of 10 mg/mL to allow precise dosing based on weight and clinical condition. It is administered intramuscularly or intravenously, depending on the severity of the infection and patient-specific factors. Dosage adjustments are required in renal impairment due to the drug’s nephrotoxic and ototoxic potential.

Adverse reactions may include nephrotoxicity, ototoxicity, neuromuscular blockade, and localized reactions at the injection site. Regular monitoring of renal function, serum drug levels, and auditory function is recommended during treatment to minimize the risk of toxicity, especially in neonates and infants.