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Description
Dutasteride 0.5 mg capsules are a pharmaceutical agent used primarily for the treatment of benign prostatic hyperplasia (BPH) in adult males. This condition involves the non-cancerous enlargement of the prostate gland, leading to urinary symptoms such as difficulty in urination, increased frequency, and decreased urine flow. Dutasteride acts by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone responsible for prostate growth.
The active mechanism of dutasteride involves dual inhibition of the type 1 and type 2 isoforms of 5-alpha-reductase. This enzyme is critical in the metabolic pathway that converts testosterone to DHT. By reducing DHT levels, dutasteride helps decrease prostate volume, improve urinary flow, and reduce the need for surgical intervention in cases of progressive BPH.
The formulation is provided in capsule form, each containing 0.5 mg of dutasteride, typically taken once daily. The medication is intended for long-term use, with therapeutic effects often observed after several months of consistent administration.
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