Additional Information

Description

Dobutamine 250 mg/20 mL SDV 10x20 mL is a synthetic sympathomimetic drug used primarily for the short-term treatment of heart failure and cardiogenic shock. It is available in a single-dose vial (SDV) containing 20 mL of solution, with a concentration of 250 mg of dobutamine per 20 mL. The product is commonly used in critical care settings, particularly in intensive care units (ICU).

The mechanism of action of dobutamine involves stimulating beta-1 adrenergic receptors in the heart, leading to increased contractility (positive inotropic effect) and heart rate (positive chronotropic effect). It has mild beta-2 adrenergic effects, which can lead to peripheral vasodilation and reduced afterload. These combined actions result in increased stroke volume and improved circulatory efficiency.

Dobutamine is administered intravenously and requires close monitoring during use. The dosage is typically adjusted based on the patient's response, aiming to optimize cardiac output without inducing excessive tachycardia. Common side effects include arrhythmias, hypertension, and increased heart rate.