Horizon™ Ligation System - The Horizon Ligation System is designed to meet the needs of surgeons, nurses, and other operating room personnel. Five clip sizes to meet all your ligation needs: Microclip ™, S, M, ML, and L - Heart-shaped wire designed to give each clip a firm grip on vessels Chevron clip shape engulfs tissue allowing precise tip-to-tip closure - Transverse grooves make clips resistant to slippage across the vessel - Available in 6- and 24-clip cartridges Convenient adhesive backing keeps clip cartridge in place System allows easy and precise clip loading - Open and endoscopic appliers available.