Additional Information

Description

Aprepitant 40 mg is a medication used to prevent nausea and vomiting caused by chemotherapy and surgery. It is a selective neurokinin-1 (NK1) receptor antagonist that works by inhibiting the binding of substance P, a neurotransmitter involved in inducing nausea and vomiting, to the NK1 receptor in the brain. This action helps reduce the occurrence of delayed nausea and vomiting following chemotherapy treatment.

Aprepitant is commonly prescribed as part of a combination regimen with other antiemetic medications, such as 5-HT3 antagonists and corticosteroids, for optimal effectiveness in managing chemotherapy-induced nausea and vomiting (CINV). It is also used for postoperative nausea and vomiting (PONV) prevention, especially after major surgeries.

The medication is typically administered in capsule form, with a recommended dose of 40 mg once daily for three days, starting one hour before chemotherapy treatment or surgery. Common side effects of Aprepitant 40 mg include fatigue, constipation, headache, and dizziness. It is important to consult a healthcare provider if any adverse reactions persist or worsen during treatment.