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Description
Amiodarone HCl Injection is a potent antiarrhythmic medication used to manage and treat serious cardiac arrhythmias, including ventricular fibrillation, ventricular tachycardia, and atrial fibrillation. The injection is provided in a single-dose vial, containing 50 mg/mL of amiodarone hydrochloride in a 3 mL volume.
Amiodarone works by inhibiting several ion channels, including sodium, potassium, and calcium channels, thus stabilizing the cardiac cell membrane and reducing abnormal heart rhythms. It prolongs the action potential duration and refractory period in cardiac tissue, which helps restore normal rhythm and prevent arrhythmias.
The injection is administered intravenously under medical supervision, particularly in critical care settings, where rapid action is required. Dosage and administration must be carefully monitored to minimize potential adverse effects, which include hypotension, bradycardia, or pulmonary toxicity. The medication is typically used in emergency situations or for patients requiring long-term management of chronic arrhythmias.
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