Additional Information

Description

Spironolactone 100 mg is a potassium-sparing diuretic primarily used to treat conditions related to excess fluid retention, such as edema associated with heart failure, liver cirrhosis, or kidney disease. Spironolactone works by antagonizing the effects of aldosterone, a hormone that promotes sodium retention and potassium excretion, thus preventing fluid buildup and maintaining potassium balance.

The mechanism of action involves binding to aldosterone receptors in the kidneys, which leads to increased sodium and water excretion while preserving potassium levels. This diuretic effect helps to reduce blood pressure and alleviate symptoms of fluid retention, such as swelling and shortness of breath.

Common side effects include hyperkalemia (elevated potassium levels), dizziness, headache, gastrointestinal discomfort, and menstrual irregularities. Serious side effects may include kidney dysfunction and severe electrolyte imbalances. Regular monitoring of kidney function and electrolytes is advised during treatment.