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Biktarvy® Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate 50 Mg - 200 Mg - 25 Mg Tablet Bottle 30 Tablets

  • Manufacturer Name : GILEAD SCIENCES
  • MFG # : 61958250101
  • NDC : 61958250101
  • Distributor Name : AmeriSource Bergen - SAGEBRUSH
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Product NameBiktarvy® Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate 50 Mg - 200 Mg - 25 Mg Tablet Bottle 30 Tablets
ApplicationHIV Integrase Inhibitor
Generic Drug NameBictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate
Mechanism of ActionBictegravir inhibits integrase, emtricitabine and tenofovir inhibit reverse transcriptase, blocking HIV replication
Dosage FormTablet
Strength50 mg Bictegravir, 200 mg Emtricitabine, 25 mg Tenofovir Alafenamide
Route of AdministrationOral
Dosing FrequencyOnce daily with or without food
Common Side EffectsDiarrhea, headache, nausea, fatigue, dizziness
PrecautionsMonitor liver and renal function, assess for any pre-existing liver disease or HIV infection
Quantity30 Tablets in bottle
IndicationsTreatment of HIV-1 infection in adults and pediatric patients weighing =25 kg

Description

Biktarvy® is a fixed-dose combination tablet containing bictegravir sodium (50 mg), emtricitabine (200 mg), and tenofovir alafenamide fumarate (25 mg). This medication is used for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 25 kg. It combines a nucleotide reverse transcriptase inhibitor (NRTI) and a non-nucleoside reverse transcriptase inhibitor (NNRTI) with an integrase strand transfer inhibitor (INSTI).

Bictegravir inhibits the integrase enzyme, preventing integration of viral DNA into the host genome. Emtricitabine and tenofovir alafenamide are NRTIs that block viral reverse transcription and replication. The combination of these three drugs offers a potent regimen with a low risk of resistance, making it suitable for treatment-naïve individuals.

Common side effects of Biktarvy® include headache, diarrhea, nausea, and fatigue. Serious adverse effects may include liver problems, kidney dysfunction, and the development of drug resistance if the regimen is not followed correctly. Regular monitoring of renal and liver function is recommended.

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Biktarvy® Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate 50 Mg - 200 Mg - 25 Mg Tablet Bottle 30 Tablets is manufactured by GILEAD SCIENCES.
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