Additional Information

Description

Metformin ER 500 mg is an extended-release formulation of metformin, an oral antidiabetic medication primarily used to manage type 2 diabetes mellitus. It works by decreasing hepatic glucose production, reducing intestinal glucose absorption, and improving insulin sensitivity. Metformin ER provides a controlled release of the drug over time, reducing the frequency of administration and minimizing gastrointestinal side effects commonly associated with the immediate-release form.

Each tablet contains 500 mg of metformin hydrochloride as the active ingredient. The extended-release formulation allows for once-daily dosing, usually with food, to improve patient adherence. The dosage is typically started low and gradually increased based on blood glucose response, with a maximum daily dose of 2,000 to 2,500 mg, depending on individual treatment needs.

Common side effects of metformin ER include gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal discomfort. Lactic acidosis is a rare but serious side effect that can occur, especially in patients with renal impairment or other contraindicating conditions. Periodic monitoring of kidney function and blood glucose levels is recommended during treatment.