Product Details
VYVGART HYTRULO SDV DROP SHIP
Manufacturer: ARGENX US INC SUBQ/DS
MFG#: 73475-3102-03
NDC: 73475-3102-03
PID: 639306
1/EA
$22,040.55
In StockAdditional Information
| Product Name | VYVGART HYTRULO SDV |
| Active Ingredient | Efgartigimod alfa and Hyaluronidase-qvfc |
| Drug Class | Neonatal Fc Receptor (FcRn) Antagonist |
| Mechanism of Action | Inhibits FcRn to reduce circulating pathogenic IgG autoantibodies |
| Strength | 1,008 mg efgartigimod alfa / 11,200 U hyaluronidase per 5.6 mL |
| Volume | 5.6 mL per single-dose vial |
| Route of Administration | Subcutaneous Injection |
| Side Effects | Injection site reactions, headache, upper respiratory tract infection |
| Precautions | Monitor for infections, hypersensitivity reactions; use in AChR+ gMG patients only |
| Storage | Refrigerate at 2°C to 8°C; do not freeze; protect from light |
| Packaging | Single-dose vial; shipped via specialty distribution (drop ship) |
| Uses | Treatment of generalized myasthenia gravis in adults with anti-AChR antibodies |
Description
VYVGART HYTRULO SDV is a subcutaneous formulation of efgartigimod alfa and hyaluronidase-qvfc, developed for the treatment of generalized myasthenia gravis (gMG) in adults who are anti-acetylcholine receptor (AChR) antibody positive. This innovative therapy modulates the neonatal Fc receptor (FcRn), reducing pathogenic IgG autoantibodies responsible for the symptoms of gMG.
The formulation combines efgartigimod alfa, a human IgG1-derived Fc fragment, with recombinant human hyaluronidase PH20. Hyaluronidase facilitates the dispersion and absorption of the biologic agent in the subcutaneous tissue, enabling an alternative to intravenous administration. This combination enhances patient convenience and allows for consistent systemic exposure with less frequent dosing.
VYVGART HYTRULO is administered via subcutaneous injection and is intended for use under the guidance of a healthcare professional. The dosing schedule typically consists of weekly administrations for four weeks per treatment cycle. The product is supplied through specialty distribution as a drop ship to maintain cold chain integrity and ensure proper handling.
Frequently Asked Questions (FAQs)
The cost of VYVGART HYTRULO SDV DROP SHIP is $$22,040.55
VYVGART HYTRULO SDV DROP SHIP is manufactured by ARGENX US INC SUBQ/DS.
You can purchase VYVGART HYTRULO SDV DROP SHIP on our website at https://supplies.pipelinemedical.com/product/detail/vyvgart-hytrulo-sdv-drop-ship-639021