Additional Information

Description

Verapamil 5 mg/2 mL Single-Dose Vial is a calcium channel blocker used to treat a variety of cardiovascular conditions, including hypertension, angina, and certain arrhythmias. It works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, thereby reducing the strength of heart contractions and dilating blood vessels. This results in a decrease in heart rate and blood pressure, providing relief from symptoms related to high blood pressure and angina.

The mechanism of action of verapamil involves the inhibition of L-type calcium channels in the heart and vascular smooth muscle. By blocking calcium from entering the cells, verapamil reduces myocardial contractility and vascular resistance, which in turn decreases the workload on the heart. This action helps to alleviate chest pain associated with angina and improve exercise tolerance.

Common side effects of verapamil include dizziness, bradycardia (slow heart rate), hypotension, and constipation. Caution is advised in patients with preexisting heart block, severe hypotension, or those who are taking other medications that affect heart rhythm. Regular monitoring is essential to adjust dosing as needed.