Product Details

Tagrisso 80 Mg Tablet

Manufacturer: ASTRAZENECA

MFG#: 00310-1350-30

NDC: 00310-1350-30

PID: 425843

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Additional Information

Product NameTagrisso 80 mg Tablet
ApplicationAnticancer Agent (Tyrosine Kinase Inhibitor)
Drug ClassTyrosine kinase inhibitor (TKI)
Generic Drug NameOsimertinib
Mechanism of Action Inhibits mutant EGFR (T790M) and other EGFR mutations, blocking cancer cell proliferation
Strength80 mg
TypeOral (Oral tablet)
Side EffectsDiarrhea, skin rash, fatigue, lung disease, cardiac effects
Special PrecautionsMonitor for lung issues (ILD), cardiac events, and liver function
Pregnancy CategoryCategory D (risk to fetus)
Container TypeBottle
Quantity30 Tablets
UsesTreatment of EGFR-mutated non-small cell lung cancer (NSCLC) with T790M mutation

Description

Tagrisso (osimertinib) is an oral medication used to treat non-small cell lung cancer (NSCLC) with specific mutations in the epidermal growth factor receptor (EGFR) gene, such as the T790M mutation. It is particularly indicated for patients who have experienced disease progression on previous EGFR-targeted therapies.

The active ingredient in Tagrisso, osimertinib, is a third-generation tyrosine kinase inhibitor (TKI). By binding to and inhibiting the mutated EGFR, it prevents the proliferation of cancer cells, ultimately slowing disease progression and improving patient outcomes. Its selective inhibition helps minimize effects on normal, non-cancerous cells, which improves the tolerability of the drug.

Common side effects of Tagrisso include diarrhea, skin rashes, and fatigue. Patients may also experience more severe adverse reactions like interstitial lung disease or cardiac issues, which necessitate prompt medical attention.

Frequently Asked Questions (FAQs)

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Tagrisso 80 Mg Tablet is manufactured by ASTRAZENECA.

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