Product Details
RHOGAM UF PLUS PFS
Manufacturer: KEDRION BIOPHARMA INC.
MFG#: 00562-7805-05
NDC: 00562-7805-05
PID: 627303
5/BX
$747.00
Limited Quantities5/CT
$728.32
In StockAdditional Information
| Product Name | RhoGAM Ultra-Filtered Plus PFS |
| Application | Hemolytic Disease of the Newborn / Suppression of Rh Isoimmunization |
| Generic Drug Name | Rho(D) Immune Globulin (Human), Preservative-Free |
| Mechanism of Action (MOA) | Binds and removes Rh-positive erythrocytes, preventing immune sensitization |
| Strength | 1,500 IU (300 mcg) |
| Type | Intramuscular |
| Onset of Action | Immediate with peak effect in hours |
| Duration of Action | Typically effective for up to 12 weeks |
| Side Effects | Injection site reactions, mild fever, headache |
| Precautions | Monitor for allergic reactions; contraindicated in IgA deficiency with anti-IgA antibodies |
| Thimerosal Content | Thimerosal-free |
| Packaging | 5 individually packaged prefilled syringes |
| Storage Requirements | Requires Refrigeration (2°C to 8°C) |
| Indications | Antepartum prophylaxis, postpartum prophylaxis, miscarriage, amniocentesis, and transfusion-related exposure |
Description
RhoGAM Ultra-Filtered Plus Prefilled Syringe is a sterile preparation of Rho(D) Immune Globulin (Human) designed to prevent Rh sensitization in Rho(D)-negative individuals exposed to Rh-positive blood. Each single-dose syringe contains 300 mcg (1500 IU) of anti-D immunoglobulin, the standard dose for preventing maternal alloimmunization during pregnancy or after Rh-incompatible transfusion.
The mechanism of action involves the suppression of the immune response to Rh-positive red blood cells in Rh-negative individuals. The anti-D antibodies in RhoGAM bind to Rh-positive erythrocytes, promoting their removal before the recipient’s immune system can recognize and mount an immune response, thereby preventing sensitization and hemolytic disease of the fetus and newborn (HDFN) in subsequent pregnancies.
RhoGAM is thimerosal-free, reducing the risk of mercury exposure. It is administered intramuscularly and should be used within the prescribed timeframe to ensure efficacy. In cases of significant fetal-maternal hemorrhage (FMH) exceeding 15 mL of Rh-positive red blood cells, additional doses may be necessary to neutralize excess Rh-positive erythrocytes.
Frequently Asked Questions (FAQs)
The cost of RHOGAM UF PLUS PFS is $$728.32
RHOGAM UF PLUS PFS is manufactured by KEDRION BIOPHARMA INC..
You can purchase RHOGAM UF PLUS PFS on our website at https://supplies.pipelinemedical.com/product/detail/rhogam-uf-plus-pfs-627303