Additional Information

Description

Revonto (Dantrolene Sodium) IV 20 mg is a critical medication used in the treatment of malignant hyperthermia, a severe reaction to certain anesthetics. Each 65 mL vial contains 20 mg of dantrolene sodium, a muscle relaxant that effectively counteracts the rapid increase in body temperature and muscle rigidity associated with this condition. The formulation also includes 3000 mg of mannitol, which acts as a stabilizing agent, and sodium hydroxide to adjust the pH to approximately 9.5 when reconstituted.

For optimal efficacy, Revonto should be stored unreconstituted at a temperature range of 20 to 25 degrees Celsius (68 to 77 degrees Fahrenheit). This storage condition helps maintain the stability and potency of the medication. Prior to administration, the product must be reconstituted with 60 mL of sterile water for injection USP, which is essential for preparing the solution for intravenous use.

Revonto's specific formulation and preparation guidelines ensure that the medication is both effective and safe for use in managing acute episodes of malignant hyperthermia. Its careful composition and handling instructions are critical for achieving the desired therapeutic outcomes in emergency medical settings.