Product Details
NALOXONE HCL 0.4MG-ML MDV 10 ML
Manufacturer: Akorn
MFG#: 17478-0042-10
NDC: 17478-0042-10
PID: 310910
Additional Information
| Product Name | Naloxone HCl 0.4 mg/mL MDV 10 mL |
| Application | Opiate Antagonist |
| Generic Drug Name | Naloxone HCl, Preservative Free |
| Mechanism of Action | Competitive opioid receptor antagonist |
| Strength | 0.4 mg / mL |
| Volume | 10 mL |
| Dosage Form | Injection |
| Administration Route | Intramuscular (IM), Intravenous (IV), Subcutaneous (SC) |
| Onset of Action | IV: 1-2 min; IM/SC: 2-5 min |
| Duration of Action | 30-90 minutes |
| Adverse Effects | Nausea, vomiting, sweating, tachycardia, hypertension, withdrawal symptoms |
| Storage Conditions | Store at 15°C–30°C (59°F–86°F); protect from light; do not freeze |
| Packaging | Sterile multi dose vial with rubber stopper |
| Indications | Opioid overdose reversal, opioid-induced respiratory depression |
Description
Naloxone HCl 0.4 mg/mL MDV 10 mL is an opioid antagonist used to reverse the effects of opioid overdose, including respiratory depression, sedation, and hypotension. It works by competitively binding to opioid receptors in the central nervous system, displacing opioids without activating the receptors. This results in the rapid restoration of normal breathing in cases of opioid-induced respiratory depression.
The medication is administered via intravenous (IV), intramuscular (IM), or subcutaneous (SC) injection, depending on the urgency of the situation. Intravenous administration provides the most rapid onset of action, typically within 1 to 2 minutes, while IM and SC routes may take up to 5 minutes. The duration of action varies but generally lasts between 30 to 90 minutes.
Naloxone is indicated for opioid overdose reversal, postoperative opioid-induced respiratory depression, and opioid-induced neonatal respiratory depression. Caution is advised when administering the drug, as it may precipitate acute opioid withdrawal symptoms, including agitation, tachycardia, nausea, vomiting, and sweating.
Frequently Asked Questions (FAQs)
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NALOXONE HCL 0.4MG-ML MDV 10 ML is manufactured by Akorn.
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