Product Details
1/UN
$5,660.61
In StockAdditional Information
| Product Name | Imfinzi 500 mg/10 mL Vial |
| Active Ingredient | Durvalumab |
| Drug Class | Immune Checkpoint Inhibitor (Anti-PD-L1 Monoclonal Antibody) |
| Mechanism of Action | Blocks PD-L1, enhancing T-cell activation and immune response against tumors |
| Strength | 500 mg per 10 mL |
| Volume | 10 mL |
| Route of Administration | Intravenous infusion |
| Side Effects | Fatigue, rash, diarrhea, nausea, immune-mediated adverse events (e.g., pneumonitis, colitis, hepatitis) |
| Precautions | Risk of immune-related adverse reactions, monitor for pneumonitis, hepatitis, and colitis |
| Storage | Refrigerate at 2°C to 8°C; protect from light; do not freeze |
| Packaging | Single-use vial containing sterile, preservative-free solution |
| Uses | Treatment of non-small cell lung cancer and urothelial carcinoma |
Description
Imfinzi 500 mg/10 mL vial contains durvalumab, a fully human monoclonal antibody targeting programmed death ligand-1 (PD-L1). By binding to PD-L1, Imfinzi blocks its interaction with PD-1 and CD80, which are inhibitory receptors on T-cells. This mechanism of action enhances T-cell activation and allows for a more robust immune response against cancer cells.
The drug is primarily used in the treatment of non-small cell lung cancer (NSCLC) and urothelial carcinoma, either as monotherapy or in combination with other chemotherapies or immunotherapies. It is specifically indicated for patients with unresectable stage III NSCLC who have not progressed following concurrent platinum-based chemotherapy and radiation therapy.
Common side effects include fatigue, rash, diarrhea, and nausea, while severe immune-related events may involve pneumonitis, colitis, hepatitis, and endocrinopathies. The drug should be stored refrigerated at 2°C to 8°C, protected from light, and not frozen.
Frequently Asked Questions (FAQs)
The cost of IMFINZI 500 MG/10 ML VIAL is $$5,660.61
IMFINZI 500 MG/10 ML VIAL is manufactured by Astra.
You can purchase IMFINZI 500 MG/10 ML VIAL on our website at https://supplies.pipelinemedical.com/product/detail/imfinzi-500-mg-10-ml-vial-639454