Product Details
GRANIX 480 MCG/0.8 ML SAFE SYR
Manufacturer: TEVA PHARMACEUTICALS USA
MFG#: 63459-0912-11
NDC: 63459-0912-11
PID: 639453
1/UN
$152.38
In StockAdditional Information
| Product Name | Granix 480 Mcg/0.8Ml Safe Syr |
| Active Ingredient | Tbo-Filgrastim |
| Mechanism of Action | Stimulates neutrophil production by binding to G-CSF receptors |
| Strength | 480 mcg per 0.8 mL |
| Route of Administration | Subcutaneous (SC) |
| Dosing Frequency | Once daily, typically starting 24 hours after chemotherapy |
| Common Side Effects | Bone pain, headache, injection site reactions, fatigue |
| Serious Risks | Splenic rupture, acute respiratory distress syndrome, capillary leak syndrome |
| Precautions | Monitor complete blood counts, assess for signs of splenic rupture |
| Monitoring Parameters | Neutrophil count, signs of infection, potential allergic reactions |
| Packaging | Single-use prefilled syringe |
| Storage Conditions | Store at 2°C to 8°C (36°F to 46°F), protect from light |
| Usage | Reduces risk of infection in patients receiving myelosuppressive chemotherapy |
Description
Granix (tbo-filgrastim) 480 mcg/0.8 mL is a recombinant human granulocyte colony-stimulating factor (G-CSF) analog. It stimulates neutrophil production in patients with chemotherapy-induced neutropenia, reducing the incidence of infection-related complications. The medication binds to G-CSF receptors on hematopoietic cells, promoting the proliferation, differentiation, and activation of neutrophils.
Granix is administered as a subcutaneous injection, with dosing typically initiated 24 hours after chemotherapy. The recommended dose for adults is 5 mcg/kg per day until an adequate neutrophil count is achieved. The injection should be given in the abdomen, upper arm, or thigh, rotating sites to minimize irritation. The prefilled syringe allows for precise dosing and reduces the risk of contamination.
Adverse effects include bone pain, headache, injection site reactions, and fatigue. Serious risks involve splenic rupture, acute respiratory distress syndrome, and capillary leak syndrome. Regular monitoring of complete blood counts is necessary to assess neutrophil levels and detect any hematologic abnormalities.
Frequently Asked Questions (FAQs)
The cost of GRANIX 480 MCG/0.8 ML SAFE SYR is $$152.38
GRANIX 480 MCG/0.8 ML SAFE SYR is manufactured by TEVA PHARMACEUTICALS USA.
You can purchase GRANIX 480 MCG/0.8 ML SAFE SYR on our website at https://supplies.pipelinemedical.com/product/detail/granix-480-mcg-0-8-ml-safe-syr-639453