Product Details
Estradiol Vaginal Topical Cream 2.5mg/ml x 15ml
Manufacturer: The Pharmacy Hub
MFG#: C11881
NDC: C11881
PID: 639203
Additional Information
| Product Name | Estradiol Vaginal Topical Cream 2.5 mg/mL x 15 mL |
| Generic Name | Estradiol |
| Mechanism of Action | Binds to estrogen receptors; restores local estrogen activity in vaginal tissue |
| Strength | 2.5 mg/mL |
| Form | Vaginal Topical Cream |
| Quantity | 15 mL |
| Instructions for use | Apply 0.25g - 0.5g intravaginally daily at bedtime or as directed |
| Safety information | Headache, breast tenderness, nausea |
| Warnings | Increased risk of endometrial cancer; use with progestin in women with intact uterus |
| Contraindications | Undiagnosed vaginal bleeding, estrogen-dependent tumors, active thromboembolism |
| Monitoring Parameters | Vaginal response, signs of systemic estrogen effects |
| Drug Interactions | May interact with CYP3A4 inhibitors |
| Storage Conditions | Store at room temperature |
| Shelf Life | 180 days after dispensing |
| Precautions | Use with progestin in women with intact uterus; evaluate regularly |
| Indications | Vulvar and vaginal atrophy due to menopause |
| Off-label use | Vaginal dryness, urinary symptoms |
Description
Estradiol Vaginal Topical Cream 2.5 mg/mL is indicated for the treatment of vulvar and vaginal atrophy associated with menopause. It replenishes local estrogen levels in vaginal tissues, improving symptoms such as dryness, irritation, burning, and dyspareunia. This formulation is intended for local intravaginal use and is not suitable for systemic hormone replacement.
The cream is applied intravaginally as directed by a healthcare provider, typically in a cyclic or continuous regimen. Treatment is individualized based on symptom severity and patient response. Caution is advised in prolonged use, especially in women with an intact uterus, due to the increased risk of endometrial hyperplasia and cancer.
Common adverse effects include headache, breast tenderness, and nausea. Other symptoms may include localized irritation or discharge. Estradiol may interact with CYP3A4 inhibitors, potentially increasing systemic estrogen exposure. Use should be avoided in individuals with active thromboembolic disorders, undiagnosed vaginal bleeding, or known estrogen-dependent tumors.
Frequently Asked Questions (FAQs)
The cost of Estradiol Vaginal Topical Cream 2.5mg/ml x 15ml is $available for registerd members only
Estradiol Vaginal Topical Cream 2.5mg/ml x 15ml is manufactured by The Pharmacy Hub.
You can purchase Estradiol Vaginal Topical Cream 2.5mg/ml x 15ml on our website at https://supplies.pipelinemedical.com/product/detail/estradiol-vaginal-topical-cream-2-5mg-ml-x-15ml-639203