Product Details
DOCETAXEL 20 MG/ML VIAL
Manufacturer: WINTHROP US D/B/A SANOFI AVENT
MFG#: 00955-1020-01
NDC: 00955-1020-01
PID: 639447
Additional Information
| Product Name | Docetaxel 20 mg/mL Vial |
| Active Ingredient | Docetaxel |
| Drug Class | Antineoplastic, Taxane |
| Mechanism of Action | Stabilizes microtubules, inhibiting cell division and inducing apoptosis |
| Strength | 20 mg/mL |
| Dosage Form | Injectable Solution |
| Route of Administration | Intravenous (IV infusion) |
| Side Effects | Neutropenia, fluid retention, neuropathy, alopecia, nausea, hypersensitivity |
| Precautions | Pre-medicate with corticosteroids; monitor blood counts and liver function |
| Interactions | CYP3A4 inhibitors/inducers, other chemotherapy agents |
| Storage | Store at 20°C to 25°C; protect from light and freezing |
| Packaging | Single-dose vial |
| Uses | Treatment of breast, lung, prostate, gastric, and other solid tumors |
Description
Docetaxel 20 mg/mL vial is a sterile, injectable chemotherapy agent used primarily in the treatment of various malignancies including breast, lung, prostate, and gastric cancers. It belongs to the taxane class of antineoplastic drugs, which work by disrupting microtubule function during cell division, thereby inhibiting mitosis and inducing apoptosis in rapidly dividing cancer cells.
The 20 mg/mL concentration allows for precise dosing tailored to the patient’s treatment regimen. Docetaxel is administered intravenously under strict medical supervision, usually as part of combination chemotherapy protocols. The drug’s mechanism involves stabilizing the microtubule polymer and preventing its depolymerization, which ultimately arrests the cell cycle at the metaphase-anaphase transition.
Adverse effects commonly associated with docetaxel include neutropenia, fluid retention, neuropathy, alopecia, and gastrointestinal symptoms such as nausea and vomiting. Pre-medication with corticosteroids is often recommended to reduce the risk of hypersensitivity reactions and fluid retention.
Frequently Asked Questions (FAQs)
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DOCETAXEL 20 MG/ML VIAL is manufactured by WINTHROP US D/B/A SANOFI AVENT.
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