Product Details
DBQ-PROPARACAINE HCL 0.5% OPH SOLN 15ML
Manufacturer: Sandoz
MFG#: 61314-0016-01
NDC: 61314-0016-01
PID: 639343
Additional Information
| Product Name | Proparacaine HCl 0.5% Ophthalmic Solution, 15 mL |
| Active Ingredient | Proparacaine Hydrochloride |
| Drug Class | Topical Ocular Anesthetic |
| Mechanism of Action | Blocks sodium channels to inhibit nerve impulse conduction |
| Strength | 0.5% (5 mg/mL) |
| Volume | 15 mL |
| Dosage Form | Sterile ophthalmic solution |
| Route of Administration | Topical (Ocular) |
| Side Effects | Burning, stinging, redness, blurred vision, corneal damage |
| Precautions | Avoid prolonged use, not for injection, monitor for corneal toxicity |
| Storage | 15°C to 25°C (59°F to 77°F), protect from light |
| Packaging | Dropper bottle, single-patient use |
| Latex Content | Not made with natural rubber latex |
| Uses | Corneal anesthesia for tonometry, foreign body removal, short procedures |
Description
Proparacaine HCl 0.5% Ophthalmic Solution is a topical anesthetic agent used in ophthalmic procedures requiring surface anesthesia. It is formulated as a sterile solution for external ocular use and is primarily indicated for diagnostic procedures such as tonometry, gonioscopy, removal of foreign bodies, and short ophthalmic surgical interventions. The active component, proparacaine hydrochloride, belongs to the ester group of local anesthetics.
The mechanism of action involves the reversible blockade of sodium ion influx in neuronal membranes, which prevents the initiation and conduction of nerve impulses. Onset of anesthesia typically occurs within 20 seconds after instillation, with a duration of approximately 10 to 20 minutes, depending on the procedure and individual response.
Proparacaine HCl 0.5% should be administered only by trained healthcare professionals. Prolonged use or frequent administration can result in epithelial toxicity, delayed wound healing, and potential damage to ocular tissues. Common adverse effects include transient stinging, burning, conjunctival redness, and, rarely, corneal clouding or epithelial damage.
Frequently Asked Questions (FAQs)
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DBQ-PROPARACAINE HCL 0.5% OPH SOLN 15ML is manufactured by Sandoz.
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