Product Details
DACARBAZINE 200MG/20mL VL 10BX
Manufacturer: Fresenius Kabi
MFG#: 63323-0128-20
NDC: 63323-0128-20
PID: 417734
10/BX
$ *.**
Limited Quantities10/CT
$219.84
In StockAdditional Information
| Product Name | Dacarbazine 200 mg/20 mL VL 10Bx |
| Application | Antineoplastic Agent |
| Generic Drug Name | Dacarbazine, Preservative-Free |
| Mechanism of Action | Alkylates DNA after liver metabolism, causing cell death by interfering with DNA synthesis. |
| Strength | 200 mg |
| Type | Intravenous |
| Volume | 20 mL |
| Adverse Reactions | Myelosuppression, nausea, vomiting, liver dysfunction, fatigue, and flu-like symptoms. |
| Safety Profile | Cytotoxic; requires handling with care to avoid exposure during preparation and administration. |
| Precautions | Monitor for bone marrow suppression, hepatic toxicity, and allergic reactions. |
| Packaging | Box of 10 sterile, single-use vials, preservative-free. |
| Storage Requirements | Requires Refrigeration (2-8°C), protect from light |
| Indications | Metastatic melanoma, Hodgkin’s lymphoma, soft tissue sarcomas, and other solid tumors. |
Description
Dacarbazine 200 mg/20 mL is a sterile injectable solution used as an antineoplastic agent for the treatment of various types of cancer. It belongs to the class of alkylating agents and works by interfering with the DNA synthesis of rapidly dividing cancer cells. This cytotoxic action helps inhibit tumor growth, making it an effective option for specific malignancies.
The product is supplied in a box containing 10 single-use vials, each containing 200 mg of dacarbazine dissolved in 20 mL of solution. Dacarbazine is commonly utilized in the treatment of metastatic melanoma, Hodgkin's lymphoma, and sarcomas. It is often combined with other chemotherapeutic agents to enhance efficacy. The formulation is designed for intravenous administration.
Dacarbazine exhibits a unique mechanism of action by converting into active metabolites in the liver, which then alkylate the DNA, leading to cancer cell death. It has a half-life of approximately 5 hours and is excreted primarily through the kidneys. Supportive care during therapy is essential to manage potential side effects, including nausea, vomiting, myelosuppression, and liver toxicity.
Frequently Asked Questions (FAQs)
The cost of DACARBAZINE 200MG/20mL VL 10BX is $$0.00
DACARBAZINE 200MG/20mL VL 10BX is manufactured by Fresenius Kabi.
You can purchase DACARBAZINE 200MG/20mL VL 10BX on our website at https://supplies.pipelinemedical.com/product/detail/dacarbazine-200mg-20ml-vl-10bx-417734