Product Details
BLEOMYCIN 30UNIT SDV 20mL EA
Manufacturer: Pfizer
MFG#: 61703-0323-22
NDC: 61703-0323-22
PID: 417771
1/EA
$ *.**
Limited QuantitiesAdditional Information
| Product Name | Bleomycin 30 Unit SDV 20 mL Ea |
| Application | Antineoplastic Agent |
| Generic Drug Name | Bleomycin Sulfate, Preservative-Free |
| Mechanism of Action (MOA) | Induces DNA strand breaks by generating free radicals |
| Strength | 30 Units |
| Volume | 20 mL |
| Route of Administration | Intravenous, intramuscular, subcutaneous, or intrapleural |
| Side Effects | Pulmonary fibrosis, fever, skin reactions, mucositis |
| Precautions | Monitor pulmonary function; adjust dose in renal impairment |
| Reconstitution | Reconstitute with sterile water for injection prior to use |
| Storage Requirements | Requires Refrigeration |
| Packaging | Single-dose vial |
| Uses | Treats Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas |
Description
Bleomycin 30 Unit SDV 20 mL is an antineoplastic agent classified as a glycopeptide antibiotic. It is widely used in chemotherapy regimens for the treatment of various cancers, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas. Its effectiveness as part of combination therapy makes it a critical drug in oncology for addressing malignancies that respond to its unique mechanism of action.
The mechanism of action of bleomycin involves inducing breaks in DNA strands. This is achieved through its ability to chelate metal ions such as iron and generate free radicals in the presence of oxygen. These free radicals cause single- and double-strand breaks in the DNA, which inhibits cell division and leads to apoptosis in cancer cells.
Adverse effects of bleomycin may include pulmonary toxicity, mucositis, fever, and skin reactions. Pulmonary fibrosis is a potentially severe complication, particularly at higher cumulative doses. Patients receiving bleomycin require careful monitoring of respiratory function, as well as renal and hepatic function, to minimize risks.
Frequently Asked Questions (FAQs)
The cost of BLEOMYCIN 30UNIT SDV 20mL EA is $$0.00
BLEOMYCIN 30UNIT SDV 20mL EA is manufactured by Pfizer.
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