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| Product Name | Akovaz Ephedrine Sulf 50 mg SDV |
| Application | Vasopressor for Hypotension |
| Generic Drug Name | Ephedrine Sulfate |
| Mechanism of Action (MOA) | Stimulates alpha- and beta-adrenergic receptors to increase vascular tone and cardiac output |
| Strength | 50 mg/mL |
| Type | Intravenous |
| Volume | 1 mL |
| Duration of Action | Short-acting; effects last approximately 60 minutes |
| Side Effects | Tachycardia, hypertension, headache, nausea, restlessness |
| Precautions | Use cautiously in patients with cardiovascular disease or hyperthyroidism |
| Drug Interactions | Increased effects when combined with monoamine oxidase inhibitors (MAOIs) |
| Pregnancy Category | Category C: Use only if the benefit outweighs potential risks |
| Storage Requirements | Store at controlled room temperature (20-25°C); protect from light |
| Packaging Details | Supplied in single-dose vials |
| Uses | Treatment of anesthesia-related hypotension |
Description
Akovaz (Ephedrine Sulfate) 50 mg/mL is a sterile single-dose vial indicated for the treatment of clinically significant hypotension occurring in the setting of anesthesia. Ephedrine sulfate is a sympathomimetic amine that acts as a vasopressor, restoring blood pressure levels by increasing vascular tone and cardiac output.
The mechanism of action of ephedrine involves the stimulation of alpha-adrenergic and beta-adrenergic receptors. This leads to vasoconstriction, which increases systemic vascular resistance, and positive inotropic and chronotropic effects on the heart, enhancing cardiac output. These effects contribute to a rapid improvement in blood pressure during anesthesia-related hypotensive episodes.
Akovaz is contraindicated in patients with hypersensitivity to ephedrine, during situations where vasopressors are contraindicated, or in those with severe cardiac conditions such as tachyarrhythmias. Adverse effects may include tachycardia, hypertension, headache, nausea, and restlessness. Close monitoring of blood pressure, heart rate, and overall cardiovascular function is essential during administration.
Frequently Asked Questions (FAQs)
The cost of AKOVAZ EPHEDRINE SULF 50MG SDV is $$0.00
AKOVAZ EPHEDRINE SULF 50MG SDV is manufactured by EXELA PHARMA SC.
You can purchase AKOVAZ EPHEDRINE SULF 50MG SDV on our website at https://supplies.pipelinemedical.com/product/detail/akovaz-ephedrine-sulf-50mg-sdv-634985