Additional Information

Description

Actemra- Tocilizumab Injection, Solution, Concentrate 162Mg/0.9Ml contains tocilizumab, a recombinant humanized monoclonal antibody that specifically targets the interleukin-6 (IL-6) receptor. By inhibiting IL-6 signaling, it reduces inflammation and immune system overactivity. It is indicated for the treatment of rheumatoid arthritis, giant cell arteritis, polyarticular juvenile idiopathic arthritis, systemic juvenile idiopathic arthritis, and cytokine release syndrome.

The formulation is supplied as a sterile, preservative-free solution in prefilled syringe for subcutaneous injection, depending on the condition being treated. Administration should be performed under medical supervision due to the risk of serious hypersensitivity reactions. Dosage and infusion rates vary based on the patient’s weight, disease severity, and route of administration.

Common adverse effects include infections, infusion-related reactions, elevated liver enzymes, neutropenia, and gastrointestinal symptoms. Serious risks include severe infections, gastrointestinal perforation, hepatotoxicity, and demyelinating disorders. Routine monitoring of liver function, neutrophil counts, and lipid profiles is required to minimize complications.