Product Details

Zilretta® Triamcinolone Acetonide 32 mg Injection Single-Dose Vial 5 mL

Manufacturer: Pacira

MFG#: 65250-0003-01

NDC: 65250-0003-01

PID: 639019

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Additional Information

Product NameZilretta® Triamcinolone Acetonide 32 mg Injection Single-Dose Vial 5 mL
Generic NameTriamcinolone Acetonide
Drug ClassCorticosteroid
Mechanism of ActionInhibits phospholipase A2, reducing inflammatory mediator production and suppressing immune response
Strength32 mg per vial
Dosage FormMicrosphere powder for suspension
Route of AdministrationIntra-articular Injection
Common Side EffectsJoint pain, headache, injection site reactions
Serious Adverse EffectsJoint infection, hypersensitivity reactions, systemic corticosteroid effects (adrenal suppression, hyperglycemia)
Administration InstructionsReconstitute with provided diluent before intra-articular injection; use immediately
PackagingKit containing 1 vial of Zilretta® microsphere powder, 1 vial of diluent (5 mL), and 1 sterile vial adapter
Storage ConditionsStore at 2°C to 8°C (Refrigerated); protect from light; do not freeze
UsesManagement of osteoarthritis-related knee pain

Description

Zilretta (triamcinolone acetonide) is an extended-release intra-articular corticosteroid injection approved for the management of osteoarthritis-related knee pain. It is formulated with microsphere technology, allowing for sustained drug release and prolonged therapeutic effects. The corticosteroid reduces inflammation by inhibiting phospholipase A2 and suppressing the release of inflammatory mediators such as prostaglandins and leukotrienes.

Each kit includes a single-dose vial containing 32 mg of triamcinolone acetonide microsphere powder, a vial of diluent (5 mL), and a sterile vial adapter for reconstitution. The microsphere formulation ensures gradual drug release over an extended period, reducing the need for repeated injections. Zilretta should be administered by intra-articular injection only and is not intended for repeat use.

Common adverse effects include joint pain, headache, and injection site reactions. Serious complications include joint infection, hypersensitivity reactions, and systemic corticosteroid effects such as adrenal suppression or hyperglycemia. Patients should be monitored for infection and systemic corticosteroid exposure, particularly those with diabetes or immunosuppression.

Frequently Asked Questions (FAQs)

The cost of Zilretta® Triamcinolone Acetonide 32 mg Injection Single-Dose Vial 5 mL is $$0.00

Zilretta® Triamcinolone Acetonide 32 mg Injection Single-Dose Vial 5 mL is manufactured by Pacira.

You can purchase Zilretta® Triamcinolone Acetonide 32 mg Injection Single-Dose Vial 5 mL on our website at https://supplies.pipelinemedical.com/product/detail/zilretta-32mg-er-sdv-injectable-susp-kit-639019