Product Details
Additional Information
| Product Name | Tamoxifen 20 mg |
| Drug Class | Selective Estrogen Receptor Modulator (SERM) |
| Mechanism of Action | Blocks estrogen receptors in breast tissue; partial agonist in other tissues |
| Dosage | 20 mg orally once or twice daily |
| Route of Administration | Oral |
| Common Side Effects | Hot flashes, nausea, fatigue, leg cramps |
| Safety Information | Uterine malignancy, stroke, pulmonary embolism, deep vein thrombosis |
| Warnings | Signs of thromboembolism, gynecologic symptoms, INR if on warfarin |
| Drug Interactions | Warfarin (? INR); CYP2D6 inhibitors may reduce efficacy |
| Contraindications | History of DVT, PE, stroke, pregnancy |
| Special Precautions | Monitor for thromboembolic events; assess gynecologic status regularly |
| Storage Conditions | Store at room temperature, in a dry place, away from light and heat |
| Off label use | May cause gynecomastia and infertility |
| Indications | Estrogen receptor-positive breast cancer; breast cancer risk reduction |
Description
Tamoxifen 20 mg is a selective estrogen receptor modulator (SERM) primarily used in the treatment of estrogen receptor-positive (ER+) breast cancer. It is effective in both premenopausal and postmenopausal women, reducing the risk of cancer recurrence and progression.Tamoxifen is prescribed for risk reduction in women at high risk of developing breast cancer, including those with a family history or genetic predisposition.
The drug functions by binding to estrogen receptors, thereby inhibiting estrogen-mediated cell proliferation in breast tissue. However, tamoxifen exhibits partial estrogen agonist activity in other tissues, such as the endometrium. This may increase the risk of uterine malignancies, including endometrial cancer.
Tamoxifen is associated with an elevated risk of thromboembolic events, including deep vein thrombosis, stroke, and pulmonary embolism. Caution is advised in patients with a history of thromboembolic disorders. It may also cause male infertility and gynecomastia in men receiving the drug for off-label uses.
Frequently Asked Questions (FAQs)
The cost of Tamoxifen 20mg is $available for registerd members only
Tamoxifen 20mg is manufactured by AUROBINDO PHARM.
You can purchase Tamoxifen 20mg on our website at https://supplies.pipelinemedical.com/product/detail/tamoxifen-20mg-639309