Product Details
LUCENTIS 0.5MG/0.05ML PREFILLED SYRINGE
Manufacturer: GENENTECH, INC
MFG#: 50242-0080-03
NDC: 50242-0080-03
PID: 422364
Additional Information
| Product Name | Lucentis 0.5 mg/0.05 mL Prefilled Syringe |
| Application | Anti-VEGF Therapy for Retinal Disorders |
| Generic Drug Name | Ranibizumab |
| Mechanism of Action | Inhibits VEGF-A, reducing abnormal blood vessel growth and leakage in the retina |
| Strength | 0.5 mg/0.05 mL |
| Volume | 0.05 mL |
| Type | Intravitreal |
| Recommended Dosage | Typically 0.5 mg (0.05 mL) by intravitreal injection once per month |
| Half-life | ~9 days in the vitreous humor |
| Common Adverse Effects | Conjunctival hemorrhage, eye pain, increased intraocular pressure, floaters, ocular discomfort |
| Storage Conditions | Store at 2°C to 8°C (36°F to 46°F); protect from light; do not freeze |
| Container Type | Prefilled Syringe |
| Indications | Wet age-related macular degeneration (AMD), diabetic macular edema (DME), diabetic retinopathy (DR), myopic choroidal neovascularization (mCNV) |
Description
Lucentis (Ranibizumab 0.5 mg/0.05 mL) Prefilled Syringe is an anti-vascular endothelial growth factor (VEGF) agent used for the treatment of neovascular (wet) age-related macular degeneration (AMD), diabetic macular edema (DME), diabetic retinopathy (DR), myopic choroidal neovascularization (mCNV), and macular edema following retinal vein occlusion (RVO). It functions by inhibiting VEGF-A, thereby reducing abnormal blood vessel growth and leakage in the retina, which helps preserve vision.
Lucentis is supplied as a 0.5 mg/0.05 mL solution in a prefilled syringe, intended for intravitreal injection once monthly. The recommended dose varies by indication, with some patients transitioning to less frequent dosing based on clinical response. The injection should be administered by a qualified ophthalmologist under sterile conditions to minimize the risk of endophthalmitis.
Common adverse effects include conjunctival hemorrhage, eye pain, increased intraocular pressure, floaters, and ocular discomfort. Serious risks include endophthalmitis, retinal detachment, arterial thromboembolic events, and intraocular inflammation. Patients require regular intraocular pressure monitoring and retinal evaluations to assess treatment response and potential complications.
Frequently Asked Questions (FAQs)
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LUCENTIS 0.5MG/0.05ML PREFILLED SYRINGE is manufactured by GENENTECH, INC.
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