Product Details
Biktarvy® Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate 50 mg - 200 mg - 25 mg Tablet Bottle 30 Tablets
Manufacturer: GILEAD SCIENCES
MFG#: 61958-2501-01
NDC: 61958-2501-01
PID: 425656
Additional Information
| Product Name | Biktarvy® Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate 50 Mg - 200 Mg - 25 Mg Tablet Bottle 30 Tablets |
| Application | HIV Integrase Inhibitor |
| Generic Drug Name | Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate |
| Mechanism of Action | Bictegravir inhibits integrase, emtricitabine and tenofovir inhibit reverse transcriptase, blocking HIV replication |
| Dosage Form | Tablet |
| Strength | 50 mg Bictegravir, 200 mg Emtricitabine, 25 mg Tenofovir Alafenamide |
| Route of Administration | Oral |
| Dosing Frequency | Once daily with or without food |
| Common Side Effects | Diarrhea, headache, nausea, fatigue, dizziness |
| Precautions | Monitor liver and renal function, assess for any pre-existing liver disease or HIV infection |
| Quantity | 30 Tablets in bottle |
| Indications | Treatment of HIV-1 infection in adults and pediatric patients weighing =25 kg |
Description
Biktarvy® is a fixed-dose combination tablet containing bictegravir sodium (50 mg), emtricitabine (200 mg), and tenofovir alafenamide fumarate (25 mg). This medication is used for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 25 kg. It combines a nucleotide reverse transcriptase inhibitor (NRTI) and a non-nucleoside reverse transcriptase inhibitor (NNRTI) with an integrase strand transfer inhibitor (INSTI).
Bictegravir inhibits the integrase enzyme, preventing integration of viral DNA into the host genome. Emtricitabine and tenofovir alafenamide are NRTIs that block viral reverse transcription and replication. The combination of these three drugs offers a potent regimen with a low risk of resistance, making it suitable for treatment-naïve individuals.
Common side effects of Biktarvy® include headache, diarrhea, nausea, and fatigue. Serious adverse effects may include liver problems, kidney dysfunction, and the development of drug resistance if the regimen is not followed correctly. Regular monitoring of renal and liver function is recommended.
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Frequently Asked Questions (FAQs)
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Biktarvy® Bictegravir Sodium / Emtricitabine / Tenofovir Alafenamide Fumarate 50 mg - 200 mg - 25 mg Tablet Bottle 30 Tablets is manufactured by GILEAD SCIENCES.
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