Product Details

Spironolactone 100mg

Manufacturer: Lupin Pharmaceuticals, Inc.

MFG#: 69584-0854-50

PID: 639265

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Additional Information

Product NameSpironolactone 100 mg
Active IngredientSpironolactone 100 mg
Mechanism of ActionAldosterone receptor antagonist; potassium-sparing diuretic
Strength100 mg
Instructions for useTake 100 mg once or twice daily with food to reduce gastrointestinal upset
Safety informationHyperkalemia, gynecomastia, menstrual irregularities, dizziness
PrecautionsMonitor potassium levels and renal functions
Drug interactionsAvoid combining with ACE inhibitors, ARBs, or potassium supplements
ContraindicationsHyperkalemia, Addison's disease, anuria, severe renal impairment
Off-Label UseAcne and hirsutism in women
Storage ConditionsStore at room temperature
Special WarningsRegular monitoring of electrolytes and renal function is recommended
IndicationHeart failure, hypertension, edema

Description

Spironolactone 100 mg is a potassium-sparing diuretic used in the treatment of heart failure, hypertension, and edema. It works by blocking aldosterone receptors, which helps reduce fluid retention, lower blood pressure, and decrease the strain on the heart. The drug also promotes the excretion of sodium while retaining potassium, making it effective in managing fluid balance.

Common side effects include hyperkalemia (elevated potassium levels), gynecomastia (breast tissue enlargement in men), and menstrual irregularities. Patients using spironolactone should be monitored regularly for changes in potassium levels and renal function, as the medication can increase the risk of hyperkalemia, especially when used in combination with ACE inhibitors, angiotensin receptor blockers (ARBs), or potassium supplements.

Spironolactone should be taken with food to minimize gastrointestinal upset. It is contraindicated in patients with hyperkalemia, Addison’s disease, or anuria. Regular monitoring of electrolytes and renal function is essential to avoid complications associated with the medication.


 

Frequently Asked Questions (FAQs)

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Spironolactone 100mg is manufactured by Lupin Pharmaceuticals, Inc..

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