discont per maria Silikon 1000 has become increasingly more popular over the last few years as patients have longed for permanent results with lip augmentation. Silikon 1000 is a medical grade pure form of silicone which is purified polydimethylsiloxane, which has FDA approval for treatment of retinal detachment of the eye and is made by Alcon Labs (Fort Worth, Texas). It currently does not have an approval for cosmetic purposes. However, Silikon 1000 has been used as filler by cosmetic surgeons and dermatologist for over 30 years with good lasting results. Although the FDA has not specifically approved the cosmetic use of the agent, the FDA modernization act of 1997 allows licensed physicians to use these agents off label for other purposes; similar to the numerous uses for BOTOX before it was approved for cosmetic procedures.