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Methotrexate Sodium 25 mg / mL Injection Vial 2 mL

  • Manufacturer Name : Pfizer
  • MFG # : 61703035038
  • NDC : 61703035038
  • Distributor Name : AmeriSource Bergen
PID UOM Price Qty
646044 5/EA
$69.36
638225 1/BX Register For Member Price
Register For Member Price

 

Additional Information

Product NameMethotrexate 50mg/2mL W/P 5Bx
Active IngredientMethotrexate
Drug ClassAntimetabolite, Immunosuppressant
Mechanism of ActionInhibits dihydrofolate reductase, disrupting DNA synthesis and cell division
Strength50mg per 2mL
Volume2mL per vial
Side EffectsNausea, vomiting, liver toxicity, bone marrow suppression, gastrointestinal issues, hair loss
PrecautionsMonitor liver function, blood counts, and kidney function
StorageStore in a cool, dry place; protect from light;
PackagingBox of 5 vials (5Bx)
UsesTreatment of rheumatoid arthritis, psoriasis, cancers (e.g., leukemia, lymphoma), and other autoimmune diseases

Description

Methotrexate 50mg/2mL W/P 5Bx is a potent medication used in the treatment of various autoimmune disorders and cancers. This injectable formulation contains 50mg of methotrexate per 2mL, allowing for precise dosing under medical supervision. Methotrexate acts as an antimetabolite, inhibiting the enzyme dihydrofolate reductase, which is crucial in DNA synthesis. 


 

The medication is commonly prescribed for the management of rheumatoid arthritis, psoriasis, and specific types of cancers like leukemia and lymphoma. Methotrexate’s efficacy in these conditions is due to its ability to suppress the immune system, reducing inflammation and controlling abnormal cell proliferation. 

This product is packaged in a box of five vials (5Bx), each containing the methotrexate solution for injection. This packaging ensures convenience and helps healthcare providers manage dosages over time. Methotrexate injections are typically administered via subcutaneous or intramuscular routes, depending on the medical condition being treated.


 

Product Properties:

Description I
Description I
Description Methotrexate sodium inj, 5 MG
DESI Drug Ind -
DESI Drug Ind $1.21; 04/01/2017
DESI Drug Ind $1.21; 04/01/2017
DESI2 Drug Ind -
Drug Category I
Drug Category USES: Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.
Drug Category USES: Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.
Drug Type Code COMMON BRAND NAME(S): Abitrexate
Drug Type Code COMMON BRAND NAME(S): Abitrexate
Drug Type Code 1
FDA Approval Date 09/30/1990
FDA Therap Equiv AP
HCPCS J9250
HCPCS 1
HCPCS 1
Market Entry Date 10/01/1990
Medical Coverage -
Medical Coverage COVERED WITH SPECIAL INSTRUCTIONS
Medical Coverage -
Termination Date (meth-oh-TREX-ate)
Termination Date (meth-oh-TREX-ate)
Termination Date -
Unit ML
Units Per Pkg 10
Active Ingredients 2645 methotrexate sodium 7413345
Active Ingredients 2645 methotrexate sodium 7413345
Active Ingredients 2645 methotrexate sodium 7413345
AHFS Class 10000000 ANTINEOPLASTIC AGENTS; 92200000 IMMUNOMODULATORY AGENTS; 92360000 DISEASE-MODIFYING ANTIRHEUMATIC AGENTS; 92440000 IMMUNOSUPPRESSIVE AGENTS
AHFS Class 10000000 ANTINEOPLASTIC AGENTS; 92200000 IMMUNOMODULATORY AGENTS; 92360000 DISEASE-MODIFYING ANTIRHEUMATIC AGENTS; 92440000 IMMUNOSUPPRESSIVE AGENTS
AHFS Class 10000000 ANTINEOPLASTIC AGENTS; 92200000 IMMUNOMODULATORY AGENTS; 92360000 DISEASE-MODIFYING ANTIRHEUMATIC AGENTS; 92440000 IMMUNOSUPPRESSIVE AGENTS
DEA Class NC
DEA Class NC
DEA Class NC
Dose Form VIAL (ML)
Dose Form VIAL (ML)
Dose Form VIAL (ML)
Fine Line Class 850085008510 All Rx Products
Fine Line Class 850085008510 All Rx Products
Fine Line Class 850085008510 All Rx Products
Gen Code and Des 8798 methotrexate sodium INJECTION VIAL 25 MG/ML
Gen Code and Des 8798 methotrexate sodium INJECTION VIAL 25 MG/ML
Gen Code and Des 8798 methotrexate sodium INJECTION VIAL 25 MG/ML
Inactive Ingredients 3192 benzyl alcohol 100516
Inactive Ingredients 3192 benzyl alcohol 100516
Inactive Ingredients 3192 benzyl alcohol 100516
OMP Family -
OMP Family -
OMP Family -
Product Category RX Pharmaceuticals
Product Category RX Pharmaceuticals
Product Category RX Pharmaceuticals
Strength 50MG
Strength 50MG
Strength 50MG
Common Brand Name J9250
Common Brand Name COMMON BRAND NAME(S): Abitrexate
Common Brand Name J9250
Drug Interaction -
Drug Interaction -
Drug Interaction DRUG INTERACTIONS: See also Warning section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: acitretin, asparaginase, chloramphenicol, leflunomide, other drugs that can cause kidney problems (such as cisplatin), other drugs that can cause liver problems (such as azathioprine, sulfasalazine, retinoids such as isotretinoin), penicillins, phenytoin, probenecid, procarbazine, pyrimethamine, sulfa medications, tetracyclines. Certain drugs that reduce stomach acid (proton pump inhibitors-PPIs such as esomeprazole, omeprazole, pantoprazole) may increase the amount of methotrexate in your blood. This effect may increase the risk of side effects, especially with high-dose methotrexate treatment. Ask your doctor or pharmacist for details and ways to lessen the risk of side effects.
Allocation Period Weekly
Allocation Period Weekly
Allocation Period Weekly
Case Quantity 180
Case Quantity 180
Case Quantity 180
Drug Form Pack Size 10
Drug Form Pack Size 10
Drug Form Pack Size 10
Form MULTIDOSE VIAL
Form MULTIDOSE VIAL
Form MULTIDOSE VIAL
Hazard Code -
Hazard Code -
Hazard Code -
Listed Chemical -
Listed Chemical -
Listed Chemical -
NIOSH Code NT1 ANTINEOPLASTIC DRUGS INCLUDING THOSE WITH MANUFACTURER'S SAFE HANDLING GUIDANCE (MSHG)
NIOSH Code NT1 ANTINEOPLASTIC DRUGS INCLUDING THOSE WITH MANUFACTURER'S SAFE HANDLING GUIDANCE (MSHG)
NIOSH Code NT1 ANTINEOPLASTIC DRUGS INCLUDING THOSE WITH MANUFACTURER'S SAFE HANDLING GUIDANCE (MSHG)
Orange Book AP Injectable aqueous solutions including dry powders, concentrated solutions or ready-to-use solutions are considered pharmaceutically and therapeutically equivalent if they produce the same concentration and are labeled similarly.
Orange Book AP Injectable aqueous solutions including dry powders, concentrated solutions or ready-to-use solutions are considered pharmaceutically and therapeutically equivalent if they produce the same concentration and are labeled similarly.
Orange Book AP Injectable aqueous solutions including dry powders, concentrated solutions or ready-to-use solutions are considered pharmaceutically and therapeutically equivalent if they produce the same concentration and are labeled similarly.
Retail Pack Quantity 1
Retail Pack Quantity 1
Retail Pack Quantity 1
Returnable Status Returnable
Returnable Status Returnable
Returnable Status Returnable
Special Storage Cond 00 None
Special Storage Cond 00 None
Special Storage Cond 00 None
Temp Zone 20 Cool-Store Cont Temp
Temp Zone 20 Cool-Store Cont Temp
Temp Zone 20 Cool-Store Cont Temp
Unit EA
Unit EA
Unit EA
Unit Size 5X2
Unit Size 5X2
Unit Size 5X2
How to Use -
How to Use HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start using methotrexate and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This medication is given by injection as directed by your doctor. The dosage, method of injection, and how often you receive this medication are based on your medical condition and response to treatment. For the treatment of rheumatoid arthritis or psoriasis, this medication is given by injection as directed by your doctor, usually once a week. For some conditions (such as rheumatoid arthritis), you may be taught to give yourself injections at home. In this case, learn all preparation and usage instructions from your health care professional. If you have any questions, ask your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
How to Use -
Missed Dose 10
Missed Dose MISSED DOSE: It is important to get each dose of this medication as scheduled. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Do not double the dose to catch up.
Missed Dose 10
Notes NOTES: Do not share this medication with others. Lab and/or medical tests (such as complete blood cell counts, liver and kidney function tests, pregnancy test, chest X-ray) should be done before you start using this medication and while you are using it. Keep all medical and lab appointments. Consult your doctor for more details.
Notes ML
Notes ML
Overdose AP
Overdose AP
Overdose OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include severe nausea and vomiting, and bloody stools.
Phonetic Pronunciation COVERED WITH SPECIAL INSTRUCTIONS
Phonetic Pronunciation (meth-oh-TREX-ate)
Phonetic Pronunciation COVERED WITH SPECIAL INSTRUCTIONS
Precautions -
Precautions -
Precautions PRECAUTIONS: See also Warning section. Before using methotrexate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, lung disease (such as pulmonary fibrosis), alcohol use, suppressed immune system, blood cell/bone marrow disorders, stomach/intestinal diseases (such as peptic ulcer, ulcerative colitis), any active infection (including chickenpox or recent exposure to it), folic acid deficiency. Methotrexate can make you more likely to get infections or may make current infections worse. Stay away from anyone who has an infection that may easily spread (such as chickenpox, COVID-19, measles, flu). Talk to your doctor if you have been exposed to an infection or for more details. Tell your health care professional that you are using methotrexate before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Children may be more sensitive to the side effects of this drug, especially seizures. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. This medication can affect fertility in both males and females. Ask your doctor for more details. Methotrexate must not be used during pregnancy. It may harm an unborn baby. Your doctor should do a pregnancy test before you start this medication. You should not become pregnant while using methotrexate. Women of childbearing age should ask about reliable forms of birth control while using this medication and for 6 months after the last dose. Men with female partners of childbearing age should ask about reliable forms of birth control while using this medication and for 3 months after the last dose. If you or your partner become pregnant, or think you are pregnant, talk to your doctor right away about the risks and benefits of this medication Methotrexate passes into breast milk and may harm a nursing infant. Breast-feeding is not recommended while using this drug and for at least 1 week after the end of treatment. Consult your doctor before breast-feeding.
Side Effects -
Side Effects SIDE EFFECTS: See also Warning section. Nausea, vomiting, stomach pain, drowsiness, or dizziness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Temporary hair loss may occur. Normal hair growth should return after treatment has ended. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mouth sores, diarrhea, signs of anemia (such as unusual tiredness, pale skin), signs of liver problems (such as nausea/vomiting that doesn't stop, dark urine, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone pain, unusual pain and discoloration of the skin, signs of kidney problems (such as change in the amount of urine), dry cough, muscle weakness. Get medical help right away if you have any very serious side effects, including: irregular heartbeat, vision changes, weakness on one side of the body, severe headache, neck stiffness, mental/mood changes, seizures. This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Side Effects -
Storage 09/30/1990
Storage STORAGE: Consult the product instructions and your pharmacist for storage details. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Storage 09/30/1990
Uses Methotrexate sodium inj, 5 MG
Uses USES: Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.
Uses Methotrexate sodium inj, 5 MG

Frequently Asked Questions(FAQs)

The cost of Methotrexate Sodium 25 mg / mL Injection Vial 2 mL is $0.00 .
Methotrexate Sodium 25 mg / mL Injection Vial 2 mL is manufactured by Pfizer.
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