Product Details

ILARIS 150 MG/ML VIAL

Manufacturer: Novartis

MFG#: 00078-0734-61

NDC: 00078-0734-61

PID: 424063

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Additional Information

Product NameIlaris 150 Mg/mL Vial
Active IngredientCanakinumab
Mechanism of ActionIL-1ß inhibitor; binds to interleukin-1 beta, preventing inflammatory signaling
Dosage FormLyophilized Powder for Injection
Strength150 mg/mL
Route of AdministrationSubcutaneous (SC)
Dosing FrequencyEvery 4 to 8 weeks, depending on condition
Onset of ActionGradual reduction in inflammation within days
Common Side EffectsInjection site reactions, infections, headache, dizziness
Serious RisksIncreased risk of infections, neutropenia, hypersensitivity reactions
PrecautionsAvoid live vaccines; monitor for signs of infection
Monitoring ParametersCBC, infection markers, liver function tests
Storage ConditionsRefrigerate at 2°C to 8°C (36°F to 46°F); protect from light
PackagingSingle-dose vial
UsageTreatment of IL-1ß-mediated autoinflammatory diseases

Description

Ilaris 150 mg/mL vial is a monoclonal antibody formulation containing canakinumab, designed for subcutaneous administration. It is an interleukin-1 beta (IL-1ß) inhibitor used in the treatment of autoinflammatory conditions. By selectively binding to IL-1ß, it prevents inflammatory signaling, reducing symptoms associated with excessive immune activation. The medication is indicated for periodic fever syndromes, including cryopyrin-associated periodic syndromes (CAPS), familial Mediterranean fever (FMF), and tumor necrosis factor receptor-associated periodic syndrome (TRAPS).

In systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD), Ilaris reduces systemic inflammation, fever, and joint manifestations by suppressing IL-1ß activity. It provides sustained symptom control with a single subcutaneous dose administered every four to eight weeks, depending on the condition.

Ilaris is supplied as a lyophilized powder in a single-use vial requiring reconstitution before administration. It should be prepared using sterile techniques and injected subcutaneously by a healthcare professional. Patients should be monitored for potential hypersensitivity reactions, infections, and neutropenia.

Frequently Asked Questions (FAQs)

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ILARIS 150 MG/ML VIAL is manufactured by Novartis.

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