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Fulvestrant 50Mg/Ml 5Ml Syr Fk 2/Pac

  • Manufacturer Name : Fresenius Kabi
  • MFG # : 63323071505
  • NDC : 63323071505
  • Distributor Name : Cardinal - SAGEBRUSH
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Additional Information

Product NameFulvestrant 50Mg/Ml 5Ml Syr Fk 2/Pac
Active IngredientFulvestrant
Mechanism of ActionSelective estrogen receptor degrader (SERD); binds and degrades estrogen receptors, inhibiting tumor growth
Strength50 mg/mL
Volume5 mL per syringe, 2 syringes per pack
Route of AdministrationIntramuscular (IM) injection
Side EffectsInjection site pain, nausea, fatigue, musculoskeletal pain, elevated liver enzymes, thromboembolic events
PrecautionsUse with caution in hepatic impairment, bleeding disorders, and thrombocytopenia
PackagingPrefilled syringes for accurate dosing and sterility
UsesTreatment of hormone receptor-positive metastatic breast cancer, particularly after anti-estrogen therapy failure

Description

Fulvestrant 50 mg/mL is a selective estrogen receptor degrader (SERD) used in the treatment of hormone receptor-positive metastatic breast cancer. It functions as an estrogen receptor antagonist by binding to estrogen receptors and promoting their degradation, thereby inhibiting estrogen-dependent tumor growth. This mechanism makes it effective in postmenopausal women with advanced breast cancer.

The formulation is supplied as a 5 mL solution in prefilled syringes, with each package containing two syringes. It is administered as an intramuscular injection, typically given once per month, with an initial loading dose regimen in certain cases. The drug is absorbed slowly from the injection site, ensuring sustained receptor blockade and prolonged therapeutic activity.

Common adverse effects include injection site pain, nausea, fatigue, and musculoskeletal discomfort. Serious reactions such as elevated liver enzymes, hypersensitivity reactions, and thromboembolic events may occur. Patients with hepatic impairment require dose adjustments due to the drug’s metabolism in the liver.

Frequently Asked Questions(FAQs)

The cost of Fulvestrant 50Mg/Ml 5Ml Syr Fk 2/Pac is available for registerd members only .
Fulvestrant 50Mg/Ml 5Ml Syr Fk 2/Pac is manufactured by Fresenius Kabi.
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