Product Details
Additional Information
| Product Name | Exparel 1.3% 10 mL |
| Application | Local Anesthetic |
| Generic Drug Name | Bupivacaine Liposome, Preservative Free |
| Mechanism of Action (MOA) | Bupivacaine blocks sodium channels in nerve fibers, providing local anesthesia and pain relief |
| Strength | 1.3%, 13.3 mg/mL |
| Type | Infiltration |
| Volume | 10 mL |
| Onset of Action | Immediate analgesia with prolonged pain relief due to liposomal delivery |
| Duration of Action | Extended release, providing up to 72 hours of pain control |
| Side Effects | Injection site reactions, nausea, hypotension, potential for systemic toxicity |
| Precautions | Monitor for signs of systemic toxicity, especially in cases of overdose |
| Pregnancy Category | Category C: Use only if potential benefits outweigh risks |
| Storage Conditions | Store refrigerated between 2-8°C, protect from light |
| Uses | Postsurgical analgesia, typically after orthopedic, abdominal, or soft tissue surgeries |
Description
Exparel 1.3% (bupivacaine liposome injection) is a local anesthetic used to provide postsurgical analgesia through single-dose infiltration at the surgical site. This formulation is designed to release bupivacaine gradually over an extended period, offering prolonged pain relief after surgery. The liposomal delivery system ensures that the drug is delivered directly to the target tissue, allowing for extended therapeutic effects while minimizing systemic exposure.
The active ingredient, bupivacaine, is a widely used amide-type local anesthetic that works by inhibiting sodium channels in nerve fibers, preventing the propagation of nerve impulses. This blockade leads to a loss of sensation in the affected area, providing effective pain management following surgical procedures. Exparel's unique liposomal formulation allows for a prolonged release of the anesthetic.
Exparel 1.3% is supplied in 10 mL vials, with each carton containing four vials. This medication is contraindicated in patients with hypersensitivity to bupivacaine or other amide local anesthetics. Potential side effects include local injection site reactions, as well as the risk of systemic toxicity in cases of overdose or improper administration.
Frequently Asked Questions (FAQs)
The cost of Exparel 1.3% 10mL is $available for registerd members only
Exparel 1.3% 10mL is manufactured by Pacira.
You can purchase Exparel 1.3% 10mL on our website at https://supplies.pipelinemedical.com/product/detail/exparel-1-3-10ml-417845