Acticoat antimicrobial barrier dressings work in a number of different ways Bacterial reduction. Smith and Nephews Acticoat dressings with SILCRYST nanocrystals have demonstrated a broad antimicrobial spectrum and kill rate in in vitro studies, inhibiting a wide range of pathogens, including drug-resistant bacteria such as methicillin-resistant Staphylococcus aureus MRSA and vancomycin resistant enteroccocus VRE. Fluid management - Chronic wounds can have a variety of exudate levels from low to very high. Each of Smith and Nephews Acticoat dressing has different degrees of absorbency to assist in the management of exudates, while helping to maintain an optimally moist wound-healing environment. Sustained release - SILCRYST nanocrystals release silver ions in the dressing quickly and sustain release for up to 7 days. Non-adherent design - Smith and Nephews Acticoat products allow for pain-free removal without disruption of the wound bed.